Amerigo Scientific announced the availability of its expanded line of GPCR phosphorylation immunoassay kits, designed for the quantitative detection of G protein-coupled receptor (GPCR) phosphorylation.

New York, USA - December 30, 2025 - Amerigo Scientific, a trusted provider of high-quality research tools and reagents, today announced the availability of its expanded line of GPCR phosphorylation immunoassay kits, designed for the quantitative detection of G protein-coupled receptor (GPCR) phosphorylation. These innovative kits offer researchers a fast, robust, and reliable solution to study a critical regulatory mechanism in cellular signaling, unlocking new possibilities in diagnostic development, drug efficacy evaluation, and therapeutic optimization.

GPCR phosphorylation is a pivotal process that modulates receptor activity, internalization, and interactions with downstream effectors, playing a key role in both physiological and pathological pathways. The ability to accurately measure phosphorylation levels provides critical insights into disease mechanisms, drug-target interactions, and resistance patterns—making it indispensable for fields ranging from neuroscience and oncology to immunology and metabolic research. Unlike traditional methods requiring western blot analysis, Amerigo Scientific's assay kits are fully compatible with multi-well plates, streamlining workflows through immunoprecipitation of affinity-labeled receptors using magnetic beads and detection with phosphosite-specific antibodies as phosphorylation biosensors.

The comprehensive product range covers 16 major GPCR families, including:

1. Adrenoceptors (α and ß subtypes), critical for cardiovascular function and neurotransmission

2. Bombesin Receptors (BB1, BB2, BB3), involved in cell proliferation and metabolic homeostasis

3. Cannabinoid Receptors (CB1, CB2), regulators of neurotransmission, immune responses, and pain perception

4. Dopamine Receptors (D1-D5), targets for Parkinson's disease and schizophrenia research

5. Opioid Receptors (MOP, DOP, KOP, ORL1), key to pain management and addiction studies

6. And other essential families such as Complement Receptors, Formylpeptide Receptors, Neuropeptide Y Receptors, and Vasopressin Receptors

Each kit is optimized for specific receptor subtypes and phosphosites, with all products offered in 96-well formats to support high-throughput screening. For example, the ß2 Adrenoceptor kits target phosphosites S355/S356 and T360/S364, while the BB3 Bombesin Receptor kits focus on T360/S361 and T363/T364—addressing the unique phosphorylation dynamics of each receptor. The kits enable researchers to elucidate mechanisms such as receptor desensitization, ligand-mediated activation, and signaling cascades, supporting the development of novel therapeutics for conditions including obesity, inflammation, neurological disorders, and cardiovascular diseases.

Amerigo Scientific's commitment to quality and innovation is reflected in the design of these kits, which combine specificity, sensitivity, and ease of use to support both basic research and translational applications. Whether evaluating drug candidates, studying disease models, or exploring cellular signaling pathways, the kits provide a standardized platform for reproducible results.

For more information about Amerigo Scientific's GPCR phosphorylation immunoassay kits, including detailed product specifications and ordering details, visit Amerigo Scientific's website at www.amerigoscientific.com or contact the company's customer support team.

About Amerigo Scientific

Amerigo Scientific is a leading supplier of research reagents, tools, instruments, and services for the global scientific community. With a focus on providing high-quality, innovative products, the company supports researchers in academia, the pharmaceutical, and biotech industries across a wide range of disciplines, including molecular biology, biochemistry, immunology, and drug discovery. By combining technical expertise with customer-centric service, Amerigo Scientific aims to accelerate scientific progress and enable breakthrough discoveries.

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